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Sunday, March 5, 2017

The health-promoting potential of Dendrobium species (Orchidaceae)

Abstract (as presented by the authors of the scientific work):

"Dendrobium species, commonly known as "Shihu" or "Huangcao," represents the second largest genus of Orchidaceae, which are used commonly as tonic herbs and healthy food in many Asian countries. The aim of this paper is to review the history, chemistry, and pharmacology of different Dendrobium species on the basis of the latest academic literatures found in Google Scholar, PubMed, Sciencedirect, Scopus, and SID."

Covered topics (the letter size corresponds to the frequency of mentioning in the text):

Conclusion (as presented by the authors of the scientific work):

"In this paper, the history, chemistry, and pharmacology of different Dendrobium species are reviewed. Especially for biological pharmacology (Table 7). The pharmacological activities examined include antioxidant, anti-inflammatory, immunomodulatory, antitumor, antimicrobial/antifungal, antimutagenic activities, and antiplatelet aggregation activities. The ABTS, DPPH, and hydroxyl radical scavenging effects of different polysaccharides such as DNP, DNP2-1, DNP1-1, DNP3-1, and DNP4-2 have been investigated. Loddigesiinol, nobilone, dihydrophenanthrenes, and phenanthrenes have been evaluated for nitric oxide (NO) scavenging effect. Five types of polysaccharides from D. huoshanense, D. chrysotoxum, and D. fimbriatum species were compared. D. huoshanense and D. chrysotoxum polysaccharides exhibited stronger DPPH and hydroxyl scavenging activity while D. fimbriatum polysaccharides have stronger ABTS scavenging activity. Dihydrophenanthrenes and loddigesiinol D were isolated from D. loddigesii and D. nobile species. Dihydrophenanthrenes significantly inhibited DPPH production. Loddigesiinol D significantly inhibited NO production."

Full-text access of the referenced scientific work:

Lam Y, Ng TB, Yao RM, Shi J, Xu K, Sze SC, Zhang KY. Evaluation of chemical constituents and important mechanism of pharmacological biology in dendrobium plants. Evid Based Complement Alternat Med. 2015;2015:841752. doi: 10.1155/2015/841752. Review. PubMed PMID: 25945114; PubMed Central PMCID: PMC4402476.


Prof. Atanas G. Atanasov (Dr. habil., PhD)

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