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Amorpha fruticosa: noxious invasive alien or a promising therapeutic?


Abstract (as presented by the authors of the scientific work):

"Amorpha fruticosa L. (Fabaceae) is a shrub native to North America which has been
cultivated mainly for its ornamental features, honey plant value and protective properties
against soil erosion. It is registered amongst the most noxious invasive species in
Europe. However, a growing body of scientific literature also points to the therapeutic
potential of its chemical constituents. Due to the fact that A. fruticosa is an aggressive
invasive species, it can provide an abundant and cheap resource of plant chemical
constituents which can be utilized for therapeutic purposes. Additionally, exploitation of
the biomass for medicinal use might contribute to relieving the destructive impact of
this species on natural habitats. The aim of this review is to provide a comprehensive
summary and systematize the state-of-the-art in the knowledge of the phytochemical
composition and the potential of A. fruticosa in disease treatment and prevention, with
especial emphasis on diabetes and metabolic syndrome. Also reviewed are aspects
related to potential toxicity of A. fruticosa which has not yet been systematically
evaluated in human subjects."


Representative image (based on Figure 3 of the publication):


Amorpha fruticosa: noxious invasive alien or a promising therapeutic image based on Figure 3


Conclusions (as presented by the authors of the scientific work):

"The different effects of Amorpha fruticosa reviewed in this work are outlined in Figure 4. The potential of Amorpha fruticosa against diabetes and metabolic disease is promising and deserves further investigation. The toxicity review in relation to safety application revealed that until now there are no published data about human toxicity of A. fruticosa. On the contrary A. fruticosa and compounds isolated from it showed many positive and useful effects for humans. This aggressive invasive species provides endless, cheap resource which can be utilized for remedial purposes. A vast use of A. fruticosa substances in the future might contribute to resolve problems associated with this aggressive invasive species in the natural habitats in many European countries."


Full-text access of the referenced scientific work:

Kozuharova E, Matkowski A, Woz´niak D, Simeonova R, Naychov Z, Malainer C, Mocan A,
Nabavi SM and Atanasov AG (2017) Amorpha fruticosa – A Noxious Invasive Alien Plant in Europe or a Medicinal Plant against Metabolic Disease? Front. Pharmacol. 8:333. doi: 10.3389/fphar.2017.00333
https://www.researchgate.net/publication/317411495_Amorpha_fruticosa_-_A_Noxious_Invasive_Alien_Plant_in_Europe_or_a_Medicinal_Plant_against_Metabolic_Disease


Webmaster:

Prof. Atanas G. Atanasov (Dr. habil., PhD)
https://about.me/Atanas_At


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